High prevalence of HPV Infections among women living with HIV on a longitudinal clinic
C. Zorrilla1, V. Tamayo-Agrait1, A.M. Scorsone2, H. Venegas-Rios3, I. Febo-Vazquez2, A.P. Ortiz-Martinez3
1University of Puerto Rico School of Medicine, Obstetrics and Gynecology, San Juan, Puerto Rico, 2Maternal Infant Studies Center (CEMI); UPR School of Medicine, Obstetrics and Gynecology, San Juan, Puerto Rico, 3UPR School of Public Health, Epidemiology and Biostatistics, San Juan, Puerto Rico
Background: According to the CDC, Human Papillomavirus (HPV) is the most common sexually transmitted infection in the United States, with approximately 6.2 million newly diagnosed and 20 million people with active infections each year in the USA. The prevalence rates among women living with HIV can range from 36.3% to 97.1%; according to specific samples' risk behaviors, location, and sample size compared with 27% for uninfected women 14-59 yrs. The prevalence of HPV in Puerto Rico is unknown.
Methods: This is a cross-sectional study with a sample size of 320 consecutive women attending the Maternal Infant Studies Center at the University of PR. Data was collected on HPV positivity, cervical cytology, HPV risk/co-factors, and HIV information through assisted self-administered questionnaires, gynecological examination, HPV-PCR linear array genotyping, and blood samples.
Results: Preliminary prevalence, based on HPV samples for 91 women was 59.6%, with 31.5% being HR-HPV types and 55.1% LR-HPV types. The mean age was 38 years, (21-62 years). 27.4% completed High School, 7.4% vocational/technical courses, and 16.8% obtained college degree. One third (29%) had consensual partners, 27% separated/divorced, 25% single, 13% married and 6% widows; 44% earn less than $300/month.
Conclusions: The high prevalence of HPV/HIV co-infections among the sample warrants further investigation into risk/co-factors and HPV types present within the population.
This study was supported by NCRR 5 U54 RR19507-06
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