Influenza like illness (ILI) in an AIDS Clinic
during Influenza H1N1 outbreak in Brazil
M.I.B.F. Lopes1, A.T.W. Song1, S.P. Goulart2, C.T.G. Novaes1, E.B. Gutierrez1
1Casa da AIDS - University of São Paulo, Sao Paulo, Brazil, 2Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil
Swine influenza emerged
last year on Northern hemisphere but suddenly spread to south countries during
winter. The hallmark of this epidemic was the increased number of
hospitalizations and deaths especially in particular subsets of patients. HIV
infected patients are often classified as a more vulnerable population with
increased risk of complication. Here we describe the case presentation and
baseline characteristics and outcome of a patients evaluated with ILI during the flu
outbreak in São Paulo, Brazil.
Patients presenting with
ILI from a single AIDS Center in São Paulo with about 3300 patients in
follow-up. Patients were evaluated through a standardized form. Data about
hospitalization was compiled from an institutional database. ILI definition in
Brazil is the presence of fever (temperature > 38o.C) and cough or odinophagy.
patients presented with ILI from July to
October 2009. This represents 9,7% of total non-scheduled appointments during
this period. 56% were male, mean
age was 44 years (25-66), CD4 count
value was 570 cels/ml (SD = 270).
The most frequent symptom besides de defining criteria was mialgia referred
by 66,4% of patients, cough was present in 80,4%, and odinophagy in 52.9% of
cases. 27,7% of patients have at presentation one or more comorbidites that increase
the risk of complications (chronic respiratory diseases in 6,7%). 29,6%
have oxygen saturation below 96% but only 1,7% below 90%. 11,8% were referred
to emergency unit but only 4,2% were hospitalized with no deaths. Oseltamivir
was prescribed to 30.3% of cases. RT-PCR for H1N1 was performed on the first 19
patients and was positive in 47% of those (9patients).
Conclusions: ILI during
a Influenza outbreak in our center didn't differ from that observed in non
HIV/AIDS patients. Few patients presented with respiratory distress and there
are no deaths. Oseltamivir use could have contributed for this result.
Back to the Programme-at-a-Glance