XVIII International AIDS Conference

Abstract

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Adolescence and pregnancy among HIV infected women

C.B. Hofer1, E. Machado2, T.P. Costa3, T. Abreu3, R.H. Oliveira3, E.C. Santos4, S.A. Nogueira5

1UFRJ, Preventive Medicine - Infectious Diseases, Rio de Janeiro, Brazil, 2Universidade Federal do Rio de Janeiro, Infectious Diseases, Rio de Janeiro, Brazil, 3Universidade Federal do Rio de Janeiro, Pediatrics, Rio de Janeiro, Brazil, 4Universidade Federal do Rio de Janeiro, Preventive Medicine, Rio de Janeiro, Brazil, 5Faculdade de Medicina de Petrópolis, Pediatrics, Petrópolis, Brazil

Background: Although pregnancy is a frequent event among HIV infected women's life, pregnancy during adolescence is a problem, and in the HIV care several interventions must be tailored to this population. In this study we aimed to describe characteristics more specific from this age group, that must be evaluate while treating HIV infected pregnant women.
Methods: This is a cohort study. It followed up prospectively all HIV infected women from a reference center in Rio de Janeiro, from 1996 to 2009. We classified women aged up to 20 and 11 months as adolescents, and compared them with older women, using socio-demographic, clinical, and laboratorial characteristics. The chi-square and Student T tests were used to perform bivariate analysis, for multivariate analysis a logistic regression model was fitted.
Results: We followed up 193 adolescents and 1031 older women, 13 children were infected, and there was no difference between the two groups. The independent variables associated with being adolescents were lower:number of minimum salaries per family (OR=0.86 95%CI=0.78-0.95), baseline CD4 cell count (each 100 cells) (OR=1.09, 95%CI=1.01-1.05), gestational age at prenatal care initiation (per week) (OR=1.03, 95%CI=1.01-1.05), year of pregnancy (before or after 2000) (OR=0.68, 95%CI=0.46-1.00).
Conclusions: In our group adolescence is not a risk factor for HIV vertical transmission. Characteristics such as income and less assess to health care (delayed prenatal care initiation) must be addressed while taking care of them.


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