XVIII International AIDS Conference


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Skin changes more prevalent in HIV-infected pregnant women

M.d.L.R.C. Leite, C.R. Aguilar, R.A. Aguiar, B.M. Andrade, M.T. Tavares, M.S. Miranda, G.V. Souza, V.H. Melo

UFMG, Faculdade Medicina, Belo Horizonte, Brazil

Institution: Hospital das Clínicas of Federal University of Minas Gerais (UFMG).
Background: HIV-infection during pregnancy diagnosis is becoming more frequent in our country since we are performing a prenatal universal screening of HIV infection among Brazilian pregnant women. It is also well known that several skin manifestations are common in these patients during pregnancy. Our objective was to describe the most commonly skin and / or cutaneous signs and symptoms presented by pregnant women followed by a team of dermatologists and obstetricians.
Methods: Cross-sectional study of HIV-positive pregnant women followed at the Antenatal Care and High-risk Pregnancy and at the Dermatology Clinic (Skin and Pregnancy), at Hospital das Clínicas of Federal University of Minas Gerais, from 2008 to 2009.
Results: 80 HIV-infected pregnant women were enrolled during this time. The average maternal age was 28.9 years and the average gestational age, at the first visit, 22.4 weeks. Among them, 32 (40.0%) were Afro-Brazilians, 28 (35.0%) Black subjects and 20 (25.0%) Caucasian. At the first dermatologic consultation, 58 (72.5%) pregnant women were using antiretroviral therapy (ART) for prevention of vertical transmission of HIV. The global prevalence of skin changes was 89.0%. The xerosis (asteatosis) was the most common sign, occurring in 55 (69.0%) women, followed by rash in 33 (41.3%). Other skin changes were: atopic dermatitis, contact dermatitis, superficial, post-inflammatory hyperpigmentation, HPV and molluscum contagiosum.
Conclusion: Skin changes prevalence during pregnancy of HIV-infected women was high. These results confirm the importance of a partnership between obstetricians and dermatologists during antenatal care, which could contribute to reduce clinical complications of these lesions.

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