Cancer and AIDS. Incidence and clinical characteristic of patients from the National Oncology Center in Luanda, Angola, 2006-2007
A. de la Torres Santos1, F. Zanzambi2, A. Carr Perez3, F. Miguel4
1Celetino Hernandez Hospital, Oncology Service, Santa Clara, Cuba, 2National Cancer Center, Clinical Director, Luanda, Angola, 3Center of Molecular Immunology, Havana, Cuba, 4National Oncology Center, General Director, Luanda, Angola
Background: Sub-Saharan Africa is more heavily affected by HIV and AIDS than other region of the world; however, Angola is one of the countries with low rate (2,5%). AIDS or Non AIDS defining malignancies have been poorly studied in this area. The treatments of these patients are difficult for their poverty and inadequate health infrastructure. Angola has a unique public hospital dedicated to cancer treatment: The National Oncology Center (NOC) in Luanda. Our purpose is to show the incidence of cancer associated to AIDS and additionally, to describe the mainly clinical characteristics during 2006-2007.
Methods: Retrospective Transversal Study was designed with 1423 cancer patients treated in NOC. Different variable were studied in patients with AIDS: sex, age, tumor location, histology classification, diagnostic base, morphology and cancer treatments.
Results: 113/1423 cancer patients presented HIV associated infection. The age was lower than 44, in 84% of patients. About of 48 percent of patients were female. While Kaposi´s sarcoma was the more frequently malignancy (85%) followed by Non Hodgkin´s lymphoma (high grade) and cervix uteri cancer. Non Hodgkin´s lymphoma was the most abundant pediatric cancer among these patients. Cancer disease was the diagnosis as evolution to AIDS in the eighty-five percent while, the rest were diagnosed as AIDS with the oncological diseases. Fever neutropenia was the most frequently complication during the cancer therapy
Conclusions: Around 7-8% of cancer patients studied had HIV associated. AIDS defining malignancies were the cancer pattern found. Only 25% of HIV infected Angolan people are currently receiving ART and life expectancy is 42 years old; therefore our results matched this harsh reality. To make improvements in HIV prevention and treatment would change the outcome to these data.
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