XVIII International AIDS Conference

Abstract

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Clinical presentation of HIV-infection and AIDS in Spain: differences between immigrant and autochthonous populations

B. Roca1, J. Cosín2, P. Domingo3, M.J. Galindo4, M.L. García Alcalde5, P. Geijo6, J. Lopez-Aldeguer7, F. Lozano8, A. Muñoz9, E. Deig10, E. Ribera11, T. Sanchez12, I. Suárez-Lozano13, R. Teira14, A. Terrón15, A. Vergara16, P. Viciana17, F. Vidal18, J. Muñoz19, V. Estrada20, T. Puig21, M.A. Castaño22, E. Pedrol23, M. Garrido24

1Hospital General of Castellon, University of Valencia, Castellón, Spain, 2H. Gregorio Marañon, Madrid, Spain, 3H. S. Creu i S. Pau, Barcelona, Spain, 4H. Clinico, Valencia, Spain, 5H. de Cabueñes, Asturias, Spain, 6H. V de la Luz, Cuenca, Spain, 7H. La Fe, Valencia, Spain, 8H. de Valme, Sevilla, Spain, 9H.I. Cristina, Badajoz, Spain, 10H General, Granollers, Spain, 11H. Vall D´hebron, Barcelona, Spain, 12H. V. del Rosell, Cartagena, Spain, 13H. I. Elena, Huelva, Spain, 14H Torrelavega, Torrelavega, Spain, 15H. SAS, Jerez, Spain, 16H. Clinico Puerto Real, Cadiz, Spain, 17H. V. del Rocío, Sevilla, Spain, 18H. Joan XXIII, Tarragona, Spain, 19H. de Basurto, Bilbao, Spain, 20H. Clinico San Carlos, Madrid, Spain, 21H. Arnau de Vilanova, Lerida, Spain, 22H. Carlos Haya, Málaga, Spain, 23Xarxa Social i Sanitaria Santa Tecla, Tarragona, Spain, 24Data Management AM-VACH, Huelva, Spain

Background: Information regarding epidemiology and clinical presentation of HIV-infection and AIDS in the immigrant population in Spain is scant.
Methods: Prospective multicenter study, based on the electronic database of the Spanish VACH Cohort, a project participated by 23 hospitals throughout
the country. We assess sociodemographic and HIV-infection-related data in the patients of the Cohort, and compare results of the immigrant with those of the autochthonous populations with nonparametric tests.
Results: We include 14,499 patients, 84.1 % are Spaniards and 15.9 % natives from other countries: 165 (1.1 % of the total) from Nigeria, 163 (1.1 %) from Ecuador, 160 (1.1 %) from Colombia, 138 (1.0 %) from Argentina, 134 (0.9 %) from Portugal, and 131 (0.9 %) from Brazil.
Table 1 shows results that refer to the first two visits, except for AIDS and follow-up data that refer to the whole study period. Values are medians when not otherwise specified.

 ImmigrantAutochthonousP
Age, years33.336.1< 0.001
Gender male, %68.776.7< 0.001
HIV-risk factor, drug use, %10.648.5< 0.001
HIV-risk factor, MSM, %31.417.9< 0.001
HIV-risk factor, heterosexual, %49.024.5< 0.001
CD4 cell count, per mm33203080.176
HIV RNA, copies per ml26,91526,3030.491
AIDS cases, %22.629.5< 0.001
Follow-up, months22.147.0< 0.001
[1]

Tuberculosis was the most common AIDS-defining condition both in the immigrant and the autochthonous population, and Pneumocystis pneumonia was the second in both populations.
Conclusions: Sociodemographic features and risk factors for HIV-infection are different in the immigrant and the autochthonous populations of Spain, while most characteristics of HIV disease are similar in both groups.


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